Article
Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications.
Nature - 9 Jan 1992
McKenna R, Xia D, Willingmann P, Ilag L L, Krishnaswamy S, Rossmann M G, Olson N H, Baker T S, Incardona N L
Abstract excerpt
The mechanism of DNA ejection, viral assembly and evolution are related to the structure of bacteriophage phi X174. The F protein forms a T = 1 capsid whose major folding motif is the eight-stranded antiparallel beta barrel found in many other icosahedral viruses. Groups of 5 G proteins form 12 dominating spikes that enclose a hydrophilic channel containing some diffuse electron density. Each G protein is a tight...
Topics
- Amino Acid Sequence
- Bacteriophage phi X 174
- Capsid
- DNA, Viral
- Ion Channels
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Protein Conformation
- Viral Proteins
- Viral Structural Proteins