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Article

Characterization of thyroid hormone binding to apolipoprotein-E: localization of the binding site in the exon 3-coded domain.

Endocrinology - 1 Sept 1993

Benvenga S, Cahnmann H J, Robbins J

Abstract excerpt

Apolipoprotein-E (apoE) has been shown by noncovalent binding and photoaffinity labeling with [125I]T4 to possess a single L-T4 binding site with a K5 of about 3 x 10(7) M-1 and a relative affinity for analogs of L-T4 = D-T4 = rT3 = triiodothyroacetic acid > L-T3. T4 binding was not affected by the flavonoid EMD 21388 or heparin, but was inhibited by diclofenac = mefenamic acid > furosemide. Localization of the...

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Identifiers

PMID: 8365370
DOI: 10.1210/endo.133.3.8365370

Genes

EMD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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