Site of action of imprinted genes revealed by phenotypic analysis of parthenogenetic embryos.

Abstract excerpt

The phenotypes of early post-implantation parthenogenetic embryos were examined. The spectrum of phenotypes suggested that three stages are adversely affected by imprinting--implantation, pregastrulation, and postgastrulation. Survival of parthenogenetic embryos past these developmental blocks can be improved but not completely overcome by experimental asynchrony. These results suggest that imprinting may be...

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