Article
Imprinting and extraembryonic tissues-mom takes control.
International review of cell and molecular biology - 1 Jan 2009
Miri Kamelia, Varmuza Susannah
Abstract excerpt
Genomic imprinting is an epigenetic mechanism that silences one parental allele of a small subset of genes. Many imprinted genes exhibit this property only in extraembryonic tissues-placenta and yolk sac. This has led to the idea that imprinting in mammals coevolved with some aspect of placentation. Nevertheless, many studies of imprinting have ignored the extraembryonic tissues, the yolk sac and its precursor,...
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