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Article

Horizontal spread of an altered penicillin-binding protein 2B gene between<i>Streptococcus pneumoniae</i>and<i>Streptococcus oralis</i>

1 Jul 1993

Abstract excerpt

The region encoding the transpeptidase domain of the penicillin-binding protein 2B (PBP 2B) gene of two penicillin-resistant clinical isolates of Streptococcus oralis was > 99.6% identical in nucleotide sequence to that of a penicillin-resistant serotype 6 isolate of Streptococcus pneumoniae. The downstream 849 base pairs of these genes were identical. Analysis of the data indicates that the PBP gene has probably...

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PMID: 8354467
DOI: 10.1111/j.1574-6968.1993.tb06345.x

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