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Article

Spread of a Chromosomal Cefixime-Resistant <i>penA</i> Gene among Different <i>Neisseria gonorrhoeae</i> Lineages

23 Dec 2009

Abstract excerpt

In Neisseria gonorrhoeae, the mosaic type of penA, which encodes penicillin-binding protein 2 (PBP 2), is associated with reduced susceptibility to oral cephalosporins. To investigate the relatedness of N. gonorrhoeae clinical isolates with reduced susceptibility, we sequenced the penA genes of 32 isolates. Five different amino acid sequence types of PBP 2 were identified, but all seemed to be derivatives of...

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PMID: 20028823
DOI: 10.1128/aac.01010-09

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