Article
Nicotinic acetylcholine receptor mRNAs in myasthenic thymuses: association with intrathymic pathogenesis of myasthenia gravis.
Biochemical and biophysical research communications - 16 Aug 1993
Hara H, Hayashi K, Ohta K, Itoh N, Ohta M
Abstract excerpt
Reverse transcription and the polymerase chain reaction showed that the alpha-, beta- and gamma-subunit genes of nicotinic acetylcholine receptor (AChR) in human skeletal muscle were expressed in myasthenia gravis (MG) thymuses (3 thymomas and 7 hyperplastic thymuses). A study of the expression of these subunit mRNAs in a variety of human tissues showed that alpha-subunit mRNA was expressed in human thymus and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
