Article
Nicotinic acetylcholine receptor mRNAs in myasthenic thymuses: association with intrathymic pathogenesis of myasthenia gravis.
Biochemical and biophysical research communications - 16 Aug 1993
Hara H, Hayashi K, Ohta K, Itoh N, Ohta M
Abstract excerpt
Reverse transcription and the polymerase chain reaction showed that the alpha-, beta- and gamma-subunit genes of nicotinic acetylcholine receptor (AChR) in human skeletal muscle were expressed in myasthenia gravis (MG) thymuses (3 thymomas and 7 hyperplastic thymuses). A study of the expression o...
Topics
- Base Sequence
- Child
- Genetic Variation
- Humans
- Hyperplasia
- Molecular Sequence Data
- Muscles
- Myasthenia Gravis
- Polymerase Chain Reaction
- RNA, Messenger
- Receptors, Nicotinic
- Thymoma
- Thymus Gland
- Thymus Neoplasms
- Tissue Distribution