Article
Limited sequence divergence of HTLV-I of Indian HAM/TSP patients from a prototype Japanese isolate.
AIDS research and human retroviruses - 1 Jun 1993
Hashimoto K, Lalkaka J, Fujisawa J, Singhal B S, Machigashira K, Kubota R, Suehara M, Osame M, Yoshida M
Abstract excerpt
Nucleotide sequences of two HTLV-I proviruses isolated from Indian patients with HAM/TSP were analyzed. The sequence data of the env, pX, and LTR regions showed 98-99% homologies with the prototype HTLV-I, ATK-1, isolated from a Japanese ATL patient, indicating that HTLV-I isolates in India and Japan are similar, with minor variations. However, certain small sequences of noncoding regions in the pX and LTR showed...
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