Article
Characterization of mutant strains of Candida albicans deficient in expression of a surface determinant.
Infection and immunity - 1 Aug 1993
Chaffin W L, Collins B, Marx J N, Cole G T, Morrow K J
Abstract excerpt
Monoclonal antibody (MAb) 17E4 reacts with a surface carbohydrate determinant and agglutinates cells of Candida albicans. Using this MAb, we have isolated N-methyl-N'-nitro-N-nitrosoguanidine-induced nonagglutinating mutants. Eleven of these were characterized for the presence and expression of the surface antigen recognized by MAb 17E4 by immunoblot analysis of whole cells and by fluorescence flow cytometry....
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