Characterization of mutant strains of Candida albicans deficient in expression of a surface determinant.

doi:10.1128/iai.61.8.3449-3458.1993

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Article

Characterization of mutant strains of Candida albicans deficient in expression of a surface determinant.

Infection and immunity - 1 Aug 1993

Chaffin W L, Collins B, Marx J N, Cole G T, Morrow K J

Abstract excerpt

Monoclonal antibody (MAb) 17E4 reacts with a surface carbohydrate determinant and agglutinates cells of Candida albicans. Using this MAb, we have isolated N-methyl-N'-nitro-N-nitrosoguanidine-induced nonagglutinating mutants. Eleven of these were characterized for the presence and expression of t...

Topics

Animals
Antibodies, Monoclonal
Antigens, Fungal
Antigens, Surface
Biological Transport
Candida albicans
Flow Cytometry
Kidney
Liver
Mannans
Mice
Mice, Inbred BALB C
Mutation

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