Article
Genetic, immunologic and biotransformation studies of patients on procainamide.
Lupus - 1 Apr 1993
Adams L E, Balakrishnan K, Roberts S M, Belcher R, Mongey A B, Thomas T J, Hess E V
Abstract excerpt
This report represents follow-up observations of a unique long-term study of patients on procainamide (PA) for various cardiac arrhythmias. Serologic and clinical evaluations associated with drug-related autoimmunity were assessed and patients were characterized for factors postulated to influence susceptibility to autoimmunity, including acetylator phenotype, oxidative metabolism of PA, HLA class profile, and...
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