Article
Acetylation status is associated with serological changes but not clinically significant disease in patients receiving procainamide.
The Journal of rheumatology - 1 Aug 1999
Mongey A B, Sim E, Risch A, Hess E
Abstract excerpt
OBJECTIVE: Autoantibodies occur in the majority of patients receiving procainamide (PA) for more than one year. Slow acetylator status has been proposed to predispose to their development. We previously reported the results of serological evaluation of 52 asymptomatic patients receiving PA. The aims of this study were to follow these patients to determine the incidence of drug related lupus (DRL) and serologic...
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