Origins of polymorphism at a polypurine hypervariable locus.

doi:10.1093/nar/21.11.2563

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Article

Origins of polymorphism at a polypurine hypervariable locus.

Nucleic acids research - 11 Jun 1993

Brereton H M, Firgaira F A, Turner D R

Abstract excerpt

We present characterisation of a hypervariable locus, D8S210, mapped to the telomeric region of the short arm of chromosome 8. The locus is highly polymorphic with alleles varying in size from 1.8 kb to 24 kb. Sequence data from 7 alleles shows that the variable region is entirely polypurine on o...

Topics

Alleles
Base Sequence
Blotting, Southern
Chromosomes, Human, Pair 8
DNA
Female
Genetic Variation
Humans
Male
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
Pedigree
Polymerase Chain Reaction
Polymorphism, Genetic
Purines
Restriction Mapping
Sequence Deletion

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