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Article

The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p.

Genes & development - 15 Jan 1998

Ruegger M, Dewey E, Gray W M, Hobbie L, Turner J, Estelle M

Abstract excerpt

Genetic analysis in Arabidopsis has led to the identification of several genes that are required for auxin response. One of these genes, AXR1, encodes a protein related to yeast Aos1p, a protein that functions to activate the ubiquitin-related protein Smt3p. Here we report the identification of a...

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Identifiers

PMID: 9436980
DOI: 10.1101/gad.12.2.198
PMCID: PMC316440

Genes

SKP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9436980-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p.PMID 9436980Read ↗

The IAA1 protein is encoded by AXR5 and is a substrate of SCF(TIR1).Semantic proximity Read ↗

Mutations in the TIR1 auxin receptor that increase affinity for auxin/indole-3-acetic acid proteins result in auxin hypersensitivity.Semantic proximity Read ↗

Arabidopsis auxin-resistance gene AXR1 encodes a protein related to ubiquitin-activating enzyme E1.Semantic proximity Read ↗

Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins.Semantic proximity Read ↗

Arabidopsis SGT1b is required for SCF(TIR1)-mediated auxin response.Semantic proximity Read ↗

AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis.Semantic proximity Read ↗

Arabidopsis ROOT UVB SENSITIVE2/WEAK AUXIN RESPONSE1 is required for polar auxin transport.Semantic proximity Read ↗

Plant development is regulated by a family of auxin receptor F box proteins.Semantic proximity Read ↗

IAA8 involved in lateral root formation interacts with the TIR1 auxin receptor and ARF transcription factors in Arabidopsis.Semantic proximity Read ↗

AXR2 encodes a member of the Aux/IAA protein family.Semantic proximity Read ↗

Physcomitrella patens auxin-resistant mutants affect conserved elements of an auxin-signaling pathway.Semantic proximity Read ↗

Recessive mutation identifies auxin-repressed protein ARP1, which regulates growth and disease resistance in tobacco.Semantic proximity Read ↗

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