Article
The roles of the rod end and the tail in vimentin IF assembly and IF network formation.
The Journal of cell biology - 1 Jul 1993
McCormick M B, Kouklis P, Syder A, Fuchs E
Abstract excerpt
Using mutagenesis, we investigated the importance of two vimentin domains: (a) a highly conserved segment near the carboxy end of the alpha-helical rod, and (b) the tail, with which the rod end is known to interact. As judged by in vitro filament assembly and expression in transiently transfected cells lacking an endogenous vimentin network, the rod-tail interaction is not essential for 10 nm filament structure...
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