Article
Recent insight into intermediate filament structure.
Current opinion in cell biology - 1 Feb 2021
Eldirany Sherif A, Lomakin Ivan B, Ho Minh, Bunick Christopher G
Abstract excerpt
Intermediate filaments (IFs) are key players in multiple cellular processes throughout human tissues. Their biochemical and structural properties are important for understanding filament assembly mechanisms, for interactions between IFs and binding partners, and for developing pharmacological agents that target IFs. IF proteins share a conserved coiled-coil central-rod domain flanked by variable N-terminal 'head'...
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