Diversity of the HLA 8.1 Extended Haplotype in the Croatian Population and Identification of a Novel Allele HLA-DRB3*01:132N.

doi:10.1111/tan.70564

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Article

Diversity of the HLA 8.1 Extended Haplotype in the Croatian Population and Identification of a Novel Allele HLA-DRB3*01:132N.

HLA - 1 Feb 2026

Grubic Zorana, Maskalan Marija, Jukic Lucija, Kamenaric Marija Burek, Jankovic Katarina Stingl, Zunec Renata

Abstract excerpt

The HLA 8.1 extended haplotype is a well-defined haplotype within the HLA region, characterised by strong linkage disequilibrium (LD) and recognised as most prevalent among populations of European ancestry. Despite its significance, comprehensive data on the extended 8.1 haplotype, encompassing all nine HLA loci with high-resolution typing, remains limited. In this study we examined the structure of the 8.1...

Topics

Humans
Haplotypes
Croatia
Alleles
Linkage Disequilibrium
HLA-DRB3 Chains
Gene Frequency
Homozygote
Histocompatibility Testing

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Open in PubMed

Identifiers

PMID: 41622026
DOI: 10.1111/tan.70564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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