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Article

Diploid yeast cells yield homozygous spontaneous mutations.

Current genetics - 1 Jan 2000

Esposito M S, Bruschi C V

Abstract excerpt

A leucine-requiring hybrid of Saccharomyces cerevisiae, homoallelic at the LEU1 locus (leu1-12/leu1-12) and heterozygous for three chromosome-VII genetic markers distal to the LEU1 locus, was employed to inquire: (1) whether spontaneous gene mutation and mitotic segregation of heterozygous markers occur in positive nonrandom association and (2) whether homozygous LEU1/LEU1 mutant diploids are generated. The...

Topics

Diploidy
Genes, Fungal
Genotype
Homozygote
Mutation
Saccharomyces cerevisiae

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8319299
DOI: 10.1007/BF00312630

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