Article
Analysis of a genetic mutation in an electrophoretic variant of the human lactate dehydrogenase-B(H) subunit.
Human genetics - 1 Jun 1993
Maekawa M, Sudo K, Kitajima M, Matsuura Y, Li S S, Kanno T
Abstract excerpt
An electrophoretic variant of the lactate dehydrogenase (LDH)-B(H) subunit was discovered in a patient with diabetes mellitus. His LDH activity in serum was slightly lower than normal and the LDH isozyme pattern showed an abnormal migration indicating an LDH-B subunit variant of the fast type. Th...
Topics
- Aged
- Alleles
- Base Sequence
- DNA Mutational Analysis
- Diabetes Mellitus
- Electrophoresis, Polyacrylamide Gel
- Genetic Variation
- Hot Temperature
- Humans
- Isoenzymes
- L-Lactate Dehydrogenase
- Male
- Molecular Sequence Data
- Nucleic Acid Heteroduplexes
- Point Mutation
- Polymerase Chain Reaction