Article
A missense mutation found in human lactate dehydrogenase-B (H) variant gene.
Biochemical and biophysical research communications - 30 Apr 1990
Sudo K, Maekawa M, Ikawa S, Machida K, Kitamura M, Li S S
Abstract excerpt
A human lactate dehydrogenase-B mutant gene was isolated from a genomic DNA library constructed from a patient with unstable LDH-B (heart) subunit. The nucleotide sequences of seven protein-coding exons were determined and a single nucleotide substitution of G by A at Arg codon CGC in exon 4 was...
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- DNA
- Exons
- Humans
- L-Lactate Dehydrogenase
- Male
- Molecular Sequence Data
- Mutation
- Myocardium
- Restriction Mapping