Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion.

doi:10.1002/ijc.2910560219

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Article

Heterogeneous response to the growth factors [EGF, PDGF (bb), TGF-alpha, bFGF, IL-2] on glioma spheroid growth, migration and invasion.

International journal of cancer - 15 Jan 1994

Pedersen P H, Ness G O, Engebraaten O, Bjerkvig R, Lillehaug J R, Laerum O D

Abstract excerpt

The effects of 5 different growth factors [EGF, PDGF(bb), TGF-alpha, bFGF and IL-2] were studied on tumour spheroids obtained from 5 different human glioma cell lines (U-251MG, D-263MG, D-37MG, D-54MG, GaMG). The expression of EGF and PDGF receptors as well as the endogenous production of TGF-alp...

Topics

Animals
Blotting, Northern
Brain
Brain Neoplasms
Cell Aggregation
Cell Division
Cell Movement
Epidermal Growth Factor
Fibroblast Growth Factor 2
Glioma
Growth Substances
Interleukin-2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Invasiveness

Phenotype

Platelet-Derived Growth Factor

RNA, Messenger

Rats

Receptors, Growth Factor

Source

Open in PubMed

Identifiers

PMID: 8314309
DOI: 10.1002/ijc.2910560219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8314309-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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