Article
Different angiogenic phenotypes in primary and secondary glioblastomas.
International journal of cancer - 1 May 2006
Karcher Sibylle, Steiner Hans-Herbert, Ahmadi Rezvan, Zoubaa Saida, Vasvari Gergely, Bauer Harry, Unterberg Andreas, Herold-Mende Christel
Abstract excerpt
Primary and secondary glioblastomas (pGBM, sGBM) are supposed to evolve through different genetic pathways, including EGF receptor and PDGF and its receptor and thus genes that are involved in tumor-induced angiogenesis. However, whether other angiogenic cytokines are also differentially expressed in these glioblastoma subtypes is not known so far, but this knowledge might be important to optimize an...
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