Marked association of a RFLP for the low density lipoprotein receptor gene with obesity in essential hypertensives.

doi:10.1016/0006-291x(92)92298-c

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Article

Marked association of a RFLP for the low density lipoprotein receptor gene with obesity in essential hypertensives.

Biochemical and biophysical research communications - 15 Dec 1992

Zee R Y, Griffiths L R, Morris B J

Abstract excerpt

RFLPs at the low density lipoprotein receptor locus (LDLR) display marked linkage disequilibrium between each other. Cross-sectional analysis of a bi-alleleic ApaLI RFLP of LDLR showed that the 9.4- and 6.6-kb alleles were present in similar frequency between a group of 84 Caucasian essential hypertensive (HT) and a group of 96 normotensive subjects whose parents each had a similar blood pressure status at age >...

Topics

Alleles
Blood Pressure
Blotting, Southern
Chromosome Mapping
Chromosomes, Human, Pair 19
DNA
Deoxyribonucleases, Type II Site-Specific
Female
Gene Frequency
Genetic Variation
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Homozygote

Humans

Hypertension

Male

Middle Aged

Obesity

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 1361731
DOI: 10.1016/0006-291x(92)92298-c

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1361731-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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