Article
Differential subcellular localisation of two isoforms of p70 S6 protein kinase.
Biochemical and biophysical research communications - 28 Jan 1994
Coffer P J, Woodgett J R
Abstract excerpt
Ribosomal protein S6 phosphorylation is stimulated by a variety of hormones and growth factors. In mammalian cells the predominant S6 kinase is a 70 kDa enzyme which exists in two forms differing only in their amino terminal region. To determine whether this difference is functionally significant...
Topics
- Amino Acid Sequence
- Animals
- Cell Compartmentation
- Cell Nucleus
- Cells, Cultured
- Cytosol
- Humans
- Isoenzymes
- Molecular Sequence Data
- Mutation
- Protein Serine-Threonine Kinases
- Recombinant Proteins
