Article
Differential subcellular localisation of two isoforms of p70 S6 protein kinase.
Biochemical and biophysical research communications - 28 Jan 1994
Coffer P J, Woodgett J R
Abstract excerpt
Ribosomal protein S6 phosphorylation is stimulated by a variety of hormones and growth factors. In mammalian cells the predominant S6 kinase is a 70 kDa enzyme which exists in two forms differing only in their amino terminal region. To determine whether this difference is functionally significant we have examined the intracellular localisation of the two forms. In cells transfected with cDNA encoding the longer...
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