Allele-specific amplification for the identification of several hemoglobin variants.

doi:10.3109/03630269308997498

Back to search

Article

Allele-specific amplification for the identification of several hemoglobin variants.

Hemoglobin - 1 Oct 1993

Postnikov YuV, Molchanova T P, Huisman T H

Abstract excerpt

Eight known abnormal hemoglobins in more than 40 patients have been identified with an allele-specific amplification procedure. These are mutants of the A gamma (Hb F-Sardinia), the delta (Hb B2), the alpha (Hb G-Philadelphia), and the beta (Hbs S, C, E, D-Los Angeles, O-Arab) globin genes. Adjus...

Topics

Alleles
Base Composition
Base Sequence
Discriminant Analysis
Gene Amplification
Genetic Testing
Genotype
Globins
Hemoglobin, Sickle
Hemoglobins
Hemoglobins, Abnormal
Heterozygote
Humans
Molecular Sequence Data
Mutation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.