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Article

Basal detachment of the epidermis using dispase: tissue spatial organization and fate of integrin alpha 6 beta 4 and hemidesmosomes.

The Journal of investigative dermatology - 1 Jan 1994

Poumay Y, Roland I H, Leclercq-Smekens M, Leloup R

Abstract excerpt

Dispase has been utilized to produce basal detachment of the epidermis of human skin biopsies and to study the consequences induced afterwards during incubations of the detached tissue. Spatial reorganization of the epidermis is observed under these conditions and is characterized by disappearance of the typical basal keratinocyte layer. Immunofluorescent labelings reveal upward migration of several cells...

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PMID: 8288902
DOI: 10.1111/1523-1747.ep12371742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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