Article
Affinity ranking of influenza neuraminidase mutants with monoclonal antibodies using an optical biosensor. Comparison with ELISA and slot blot assays.
Journal of immunological methods - 12 Jan 1994
Gruen L C, McKimm-Breschkin J L, Caldwell J B, Nice E C
Abstract excerpt
A recently developed alternative to the more traditional techniques for studying antigen-antibody interactions has been examined. This method involves the use of an optical biosensor employing surface plasmon resonance detection. In this system one of the reactants is immobilized on the sensor su...
Topics
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigen-Antibody Reactions
- Biosensing Techniques
- Enzyme-Linked Immunosorbent Assay
- Immunoblotting
- Immunoglobulin Fab Fragments
- Influenza A virus
- Mutation
- Neuraminidase