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Article

Development of A4 antibody for detection of neuraminidase I223R/H275Y-associated antiviral multidrug-resistant influenza virus.

Nature communications - 9 Jul 2020

Guk Kyeonghye, Kim Hyeran, Lee Miyeon, Choi Yoon-Aa, Hwang Seul Gee, Han Gaon, Kim Hye-Nan, Kim Hongki, Park Hwangseo, Yong Dongeun, Kang Taejoon, Lim Eun-Kyung, Jung Juyeon

Abstract excerpt

The emergence and spread of antiviral drug-resistant viruses have been a worldwide challenge and a great concern for patient care. We report A4 antibody specifically recognizing and binding to the mutant I223R/H275Y neuraminidase and prove the applicability of A4 antibody for direct detection of antiviral multidrug-resistant viruses in various sensing platforms, including naked-eye detection, surface-enhanced...

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Identifiers

PMID: 32647286
DOI: 10.1038/s41467-020-17246-w
PMCID: PMC7347576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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