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A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19

25 Nov 2021

Abstract excerpt

Inflammation is a physiological process whose deregulation causes some diseases including cancer. Nuclear Factor kB (NF-kB) is a family of ubiquitous and inducible transcription factors, in which the p65/p50 heterodimer is the most abundant complex, that play critical roles mainly in inflammation. Glucocorticoid Receptor (GR) is a ligand-activated transcription factor and acts as an anti-inflammatory agent and...

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PMID: 34824310
DOI: 10.1038/s41598-021-02119-z

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