Article
Genetic contributions to quantitative lipoprotein traits associated with coronary artery disease: analysis of a large pedigree from the Bogalusa Heart Study.
American journal of medical genetics - 1 Nov 1993
Heiba I M, DeMeester C A, Xia Y R, Diep A, George V T, Amos C I, Srinivasan S R, Berenson G S, Elston R C, Lusis A J
Abstract excerpt
A pedigree of a large family with high prevalence of heart disease is subjected to association and sib-pair linkage analysis to investigate the role of 5 candidate genes in the regulation of lipoprotein metabolism and the development of coronary artery disease. At the 5% nominal significance level, the apolipoprotein B locus (APOB) was found to be linked to high-density lipoprotein cholesterol level (HDL-C),...
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