Article
[Genetic predisposition to hypercholesterolemia and coronary heart disease. DNA polymorphism in the apolipoprotein B gene as a possible cause].
Acta medica Austriaca - 1 Jan 1991
Friedl W
Abstract excerpt
It has been demonstrated in numerous studies that hypercholesterolemia is an important independent risk factor for the development of coronary heart disease. Besides exogenous factors like diet and physical exercise genetic predisposition is a major determinant of serum cholesterol levels. Apolipoprotein B-100 (apo B-100) is the protein constituent of LDL which serves as ligand to the LDL-receptor. A...
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