Role of adenosine 3':5'-monophosphate-dependent protein kinase and cAMP levels in ATP-dependent mitogenesis in Swiss 3T3 cells.

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Article

Role of adenosine 3':5'-monophosphate-dependent protein kinase and cAMP levels in ATP-dependent mitogenesis in Swiss 3T3 cells.

The Journal of biological chemistry - 7 Jan 1994

Huang N N, Wang D J, Heppel L A

Abstract excerpt

To investigate the role of cAMP-dependent protein kinase (PKA) and cAMP levels in ATP-dependent mitogenesis, Swiss 3T3 cells were transfected with an expression vector coding for (i) a mutated regulatory subunit of PKA (PKA mutant) or (ii) a yeast low Km cAMP phosphodiesterase gene (PDE mutant)....

Topics

3',5'-Cyclic-AMP Phosphodiesterases
3T3 Cells
Adenosine Triphosphate
Amino Acid Sequence
Animals
Bombesin
Cell Division
Cyclic AMP
Cyclic AMP-Dependent Protein Kinases
Mice
Molecular Sequence Data
Mutation
Platelet-Derived Growth Factor
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 8276849

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8276849-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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