The ribosome as a source of genome hypervariability?

doi:10.1016/0306-9877(93)90230-n

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The ribosome as a source of genome hypervariability?

Medical hypotheses - 1 Sept 1993

Muslimov I A

Abstract excerpt

In this report it is suggested that at early stages of evolution ribosomes were responsible for synthesizing short oligonucleotide cDNA packets which formed the protogenic tandem repetitive sequences. Ribosomal RNA (rRNA) could have been the most probable template for such a synthesis. rRNA has homology with the monomers of tandem hypervariable repetitive elements of the genome. A model for the proposed...

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