Article
The ribosome as a source of genome hypervariability?
Medical hypotheses - 1 Sept 1993
Muslimov I A
Abstract excerpt
In this report it is suggested that at early stages of evolution ribosomes were responsible for synthesizing short oligonucleotide cDNA packets which formed the protogenic tandem repetitive sequences. Ribosomal RNA (rRNA) could have been the most probable template for such a synthesis. rRNA has h...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA, Complementary
- Genetic Variation
- Humans
- Mice
- Models, Genetic
- Molecular Sequence Data
- Peptides
- RNA, Ribosomal
- Repetitive Sequences, Nucleic Acid
- Ribosomes
- Sequence Homology, Nucleic Acid