Sequence analysis of hepatitis B virus DNA in immunologically negative infection.

doi:10.1007/BF01313777

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Article

Sequence analysis of hepatitis B virus DNA in immunologically negative infection.

Archives of virology - 1 Jan 1993

Preisler-Adams S, Schlayer H J, Peters T, Hettler F, Gerok W, Rasenack J

Abstract excerpt

It was previously demonstrated that the serum of some patients without immunological evidence of HBV infection contains the virus. Here we demonstrated by sequence analysis that the serum of such a patient contained a mixed HBV population. In comparison with HBV genomes of different genotypes twenty-two nucleotide variations were found in all clones sequenced in parallel. One nucleotide variation was identified...

Topics

Base Sequence
Cloning, Molecular
DNA Primers
DNA, Viral
Genetic Variation
Genome, Viral
Hepatitis B
Hepatitis B Antigens
Hepatitis B Core Antigens
Hepatitis B Surface Antigens
Hepatitis B virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Sequence Data

Open Reading Frames

Point Mutation

Polymerase Chain Reaction

Trans-Activators

Viral Proteins

Source

Open in PubMed

Identifiers

PMID: 8257295
DOI: 10.1007/BF01313777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8257295-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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