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Article

Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo.

Nature - 9 Dec 1993

Ingham P W

Abstract excerpt

Cell patterning in the body segments of the Drosophila embryo requires activity of the segment polarity genes, a molecularly heterogeneous group defined by a generic mutant phenotype. Two of these genes, wingless (wg) and hedgehog (hh), encode proteins that enter the secretory pathway, implicating them as signals that instruct the fates of neighbouring cells. Genetic analysis has identified wg transcription as...

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PMID: 8255293
DOI: 10.1038/366560a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo.PMID 8255293Read ↗

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