Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo.

doi:10.1038/366560a0

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Article

Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo.

Nature - 9 Dec 1993

Ingham P W

Abstract excerpt

Cell patterning in the body segments of the Drosophila embryo requires activity of the segment polarity genes, a molecularly heterogeneous group defined by a generic mutant phenotype. Two of these genes, wingless (wg) and hedgehog (hh), encode proteins that enter the secretory pathway, implicatin...

Topics

Animals
Drosophila
Embryo, Nonmammalian
Embryonic and Fetal Development
Female
Fertilization
Genotype
Heat-Shock Proteins
Larva
Male
Promoter Regions, Genetic
Signal Transduction
Transcription, Genetic

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