Article
Evaluation of chimerism after bone marrow transplantation with single locus minisatellite DNA probes.
Bone marrow transplantation - 1 Sept 1993
Harano H, Maruta A, Matsuzaki M, Kanamori H, Fukawa H, Noguchi T, Miyashita H, Ogawa K, Motomura S, Kodama F
Abstract excerpt
The origin of cells in almost all allogeneic donor-recipient pairs can be determined through the use of highly polymorphic minisatellite DNA probes. Single-locus probes were cloned from hypervariable fragments in a human DNA fingerprint detected with a multi-locus probe. While each probe is highly polymorphic and locus specific, they all contain repetitive sequences. The properties of single-locus probes have...
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