Article
Evaluation of chimerism after bone marrow transplantation with single locus minisatellite DNA probes.
Bone marrow transplantation - 1 Sept 1993
Harano H, Maruta A, Matsuzaki M, Kanamori H, Fukawa H, Noguchi T, Miyashita H, Ogawa K, Motomura S, Kodama F
Abstract excerpt
The origin of cells in almost all allogeneic donor-recipient pairs can be determined through the use of highly polymorphic minisatellite DNA probes. Single-locus probes were cloned from hypervariable fragments in a human DNA fingerprint detected with a multi-locus probe. While each probe is highl...
Topics
- Adult
- Alleles
- Bone Marrow Transplantation
- DNA Fingerprinting
- DNA Probes
- DNA, Satellite
- Female
- Graft Survival
- Graft vs Host Disease
- Humans
- Leukemia
- Male
- Radiation Chimera
- Repetitive Sequences, Nucleic Acid
- Sensitivity and Specificity
