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Article

Regulation of Ped gene expression by TAP protein.

Journal of reproductive immunology - 1 Feb 2000

Ke X, Warner C M

Abstract excerpt

The Ped (Preimplantation embryo development) gene regulates fast or slow cleavage of preimplantation mouse embryos and their subsequent survival. The protein product of the Ped gene is the major histocompatibility complex (MHC) class Ib protein Qa-2. MHC class I expression on the cell surface requires the assembly within the endoplasmic reticulum (ER) of an alpha heavy chain, a beta2 microglobulin light chain,...

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PMID: 10708239
DOI: 10.1016/s0165-0378(99)00053-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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Regulation of Ped gene expression by TAP protein.PMID 10708239Read ↗

The expression pattern of the Qa-2 antigen in mouse preimplantation embryos and its correlation with the Ped gene phenotype.Semantic proximity Read ↗

Removal of Qa-2 antigen alters the Ped gene phenotype of preimplantation mouse embryos.Semantic proximity Read ↗

Preimplantation embryo development (Ped) gene copy number varies from 0 to 85 in a population of wild mice identified as Mus musculus domesticus.Semantic proximity Read ↗

Identification of two major histocompatibility complex class Ib genes, Q7 and Q9, as the Ped gene in the mouse.Semantic proximity Read ↗

Search for the bovine homolog of the murine ped gene and characterization of its messenger RNA expression during bovine preimplantation development.Semantic proximity Read ↗

Identification of the Ped gene at the molecular level: the Q9 MHC class I transgene converts the Ped slow to the Ped fast phenotype.Semantic proximity Read ↗

Painting Qa-2 onto Ped slow preimplantation embryos increases the rate of cleavage.Semantic proximity Read ↗

Analysis of litter size and weight in mice differing in Ped gene phenotype and the Q region of the H-2 complex.Semantic proximity Read ↗

Differential expression of Ped gene candidates in preimplantation mouse embryos.Semantic proximity Read ↗

Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos.Semantic proximity Read ↗

Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice.Semantic proximity Read ↗

Analysis of a 26-kb region linked to the Mhc in zebrafish: genomic organization of the proteasome component beta/transporter associated with antigen processing-2 gene cluster and identification of five new proteasome beta subunit genes.Semantic proximity Read ↗

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