Removal of Qa-2 antigen alters the Ped gene phenotype of preimplantation mouse embryos.

doi:10.1095/biolreprod47.2.271

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Article

Removal of Qa-2 antigen alters the Ped gene phenotype of preimplantation mouse embryos.

Biology of reproduction - 1 Aug 1992

Tian Z, Xu Y, Warner C M

Abstract excerpt

Embryo survival is influenced by both genetic and environmental factors. Previous research in our laboratory has identified one gene associated with embryonic survival, the Ped gene, a gene that is linked to the major histocompatibility complex (MHC) of the mouse. The Ped gene has been shown to influence the rate of preimplantation embryonic cleavage division, as well as litter size, birth weight, and weaning...

Topics

Animals
Antigens, Surface
Cell Membrane
Chromosome Mapping
Embryo, Mammalian
Embryonic Development
Enzyme-Linked Immunosorbent Assay
Female
Genes
Glycosylphosphatidylinositols
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Mice, Inbred C57BL

Mice, Inbred CBA

Mice, Nude

Organ Culture Techniques

Phenotype

Phosphatidylinositol Diacylglycerol-Lyase

Source

Open in PubMed

Identifiers

PMID: 1327207
DOI: 10.1095/biolreprod47.2.271

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1327207-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Removal of Qa-2 antigen alters the Ped gene phenotype of preimplantation mouse embryos.PMID 1327207Read ↗

The expression pattern of the Qa-2 antigen in mouse preimplantation embryos and its correlation with the Ped gene phenotype.Semantic proximity Read ↗

Regulation of Ped gene expression by TAP protein.Semantic proximity Read ↗

Identification of the Ped gene at the molecular level: the Q9 MHC class I transgene converts the Ped slow to the Ped fast phenotype.Semantic proximity Read ↗

Painting Qa-2 onto Ped slow preimplantation embryos increases the rate of cleavage.Semantic proximity Read ↗

Identification of two major histocompatibility complex class Ib genes, Q7 and Q9, as the Ped gene in the mouse.Semantic proximity Read ↗

Analysis of litter size and weight in mice differing in Ped gene phenotype and the Q region of the H-2 complex.Semantic proximity Read ↗

Differential expression of Ped gene candidates in preimplantation mouse embryos.Semantic proximity Read ↗

Preimplantation embryo development (Ped) gene copy number varies from 0 to 85 in a population of wild mice identified as Mus musculus domesticus.Semantic proximity Read ↗

Induction of embryonic major histocompatibility complex antigen expression by gamma-IFN.Semantic proximity Read ↗

HLA-G expression during preimplantation human embryo development.Semantic proximity Read ↗

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