Article
Short exposure to high salt in drinking solution leads to a cardiovascular phenotype of hypertension without changes in the blood volume of rats.
Experimental physiology - 1 Mar 2023
Gomes Paula Magalhães, Batista Julia Santos, Sá Renato Willian Martins, Antunes Vagner Roberto
Abstract excerpt
NEW FINDINGS: What is the central question of this study? Is the cardiovascular phenotype of high blood pressure observed in rats salt loaded with 2% NaCl in drinking solution a blood volume-dependent hypertension? What is the main finding and its importance? Animals exposed to 2% NaCl drinking solution develop hypertension, with dominance of sympathetic outflow and high [Na+ ] in the cerebrospinal fluid, but...
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