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Regulation of human liver cytochromes P-450 in family 3A in primary and continuous culture of human hepatocytes

1 Nov 1993

Abstract excerpt

The cytochrome P-450 3A gene family comprises the dominant forms of cytochrome P-450 found in human liver. We examined as a possible useful system for studying the regulation of cytochrome P-450 3A under controlled conditions in vitro , primary monolayer cultures of human hepatocytes and compared the results with those obtained from the study of cytochrome P-450 3A in the human hepatoblastoma cell line HepG2 or...

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PMID: 8225233
DOI: 10.1002/hep.1840180535

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