Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos.

doi:10.1242/dev.117.1.359

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Article

Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos.

Development (Cambridge, England) - 1 Jan 1993

Dawson I A, Roth S, Akam M, Artavanis-Tsakonas S

Abstract excerpt

We describe the effects of mutations in the fizzy gene of Drosophila melanogaster and show that fizzy mutations cause cells in mitosis to arrest at metaphase. We show that maternally supplied fizzy activity is required for normal nuclear division in the preblastoderm embryo and, during later embr...

Topics

Animals
Drosophila melanogaster
Epidermis
Genes
Genes, Insect
Immunohistochemistry
Metaphase
Microscopy, Electron, Scanning
Mitosis
Mutation
Nervous System

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