Article
Phenotypic alteration of glioma cells during culture.
Noshuyo byori = Brain tumor pathology - 1 Jan 1993
Imai F, Marunouchi T, Mizoguchi Y, Ogasawara M, Kanno T
Abstract excerpt
Tissue specimens and culture cells from three human gliomas (two astrocytomas and one glioblastoma) were immunohistochemically investigated, using GFAP, S-100P, vimentin, FN and TNF antibodies. Primary culture consisted of two cell types, flat cells and fibrous cells. Phenotypic alternation was observed during successive subculture. Differences between fibrous cells in astrocytoma and those in glioblastoma were...
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