Article
A single-gene explanation for the probability of having idiopathic talipes equinovarus.
American journal of human genetics - 1 Nov 1993
Rebbeck T R, Dietz F R, Murray J C, Buetow K H
Abstract excerpt
It has been hypothesized that the pathogenesis of idiopathic talipes equinovarus (ITEV, or clubfoot) is explained by genetic regulation of development and growth. The objective of the present study was to determine whether a single Mendelian gene explains the probability of having ITEV in a sample of 143 Caucasian pedigrees from Iowa. These pedigrees were ascertained through probands with ITEV. Complex...
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