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Article

Variation in CASP10 gene is associated with idiopathic talipes equinovarus.

Journal of pediatric orthopedics - 1 Jan 2000

Heck Amy L, Bray Molly S, Scott Allison, Blanton Susan H, Hecht Jacqueline T

Abstract excerpt

Idiopathic talipes equinovarus (ITEV), more commonly known as clubfoot, is a developmental deformity characterized by rigid ankle equinus, hindfoot varus, and forefoot adduction. This common birth defect is treatable, but the etiology of ITEV is largely unknown. Recently, a deletion in the chromosomal region 2q31-33 was found to be associated with clubfoot. Microsatellite markers spanning the region were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16199938
DOI: 10.1097/01.bpo.0000173248.96936.90

Genes

CASP10
CASP8
CFLAR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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