Article
Association Between TPM1 Gene Polymorphisms and Idiopathic Congenital Talipes Equinovarus Risk in a Chinese Population.
Genetic testing and molecular biomarkers - 1 May 2021
Li Jingchun, Zhu Guanghui, Kang Xiaopeng, Shen Xiantao, Chen Shunyou, Tang Shengping, Gong Qian, Li Yiqiang, Xu Hongwen
Abstract excerpt
Background: Idiopathic congenital talipes equinovarus (ICTEV) is one of the most common congenital deformities of children, and dysplasia of the striated muscle may be one of the causes of ICTEV. Previous studies have shown that polymorphisms of the rs4075583 SNP in the tropomyosin gene 1 (TPM1) were associated with ICTEV in Caucasian children. However, there are no studies investigating the correlations of TPM...
Topics
- Alleles
- Asian People
- Case-Control Studies
- Child
- Child, Preschool
- China
- Clubfoot
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans