Article
X-linked borderline mental retardation with prominent behavioral disturbance: phenotype, genetic localization, and evidence for disturbed monoamine metabolism.
American journal of human genetics - 1 Jun 1993
Brunner H G, Nelen M R, van Zandvoort P, Abeling N G, van Gennip A H, Wolters E C, Kuiper M A, Ropers H H, van Oost B A
Abstract excerpt
We have identified a large Dutch kindred with a new form of X-linked nondysmorphic mild mental retardation. All affected males in this family show very characteristic abnormal behavior, in particular aggressive and sometimes violent behavior. Other types of impulsive behavior include arson, attem...
Topics
- Adult
- Biogenic Monoamines
- Dangerous Behavior
- Female
- Genes
- Genetic Linkage
- Humans
- Intellectual Disability
- Karyotyping
- Male
- Monoamine Oxidase
- Mutation