Article
Studies using fluorescent tetrahydrochrysene estrogens for in situ visualization of the estrogen receptor in living cells.
Molecular endocrinology (Baltimore, Md.) - 1 May 1995
Miksicek R J, Carlson K E, Hwang K J, Katzenellenbogen J A
Abstract excerpt
We have analyzed four fluorescent nonsteroidal estrogens for their potential to serve as vital cytological stains to visualize the estrogen receptor (ER) in a model receptor expression system. The novel estrogen fluorophores are based on the rigidified stilbene-like structure of 5,6,11,12-tetrahydrochrysene (THC), and they embody electron-donor (hydroxyl) and electron-acceptor groups (nitrile, amide, ester, or...
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