Studies using fluorescent tetrahydrochrysene estrogens for in situ visualization of the estrogen receptor in living cells.

doi:10.1210/mend.9.5.7565806

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Article

Studies using fluorescent tetrahydrochrysene estrogens for in situ visualization of the estrogen receptor in living cells.

Molecular endocrinology (Baltimore, Md.) - 1 May 1995

Miksicek R J, Carlson K E, Hwang K J, Katzenellenbogen J A

Abstract excerpt

We have analyzed four fluorescent nonsteroidal estrogens for their potential to serve as vital cytological stains to visualize the estrogen receptor (ER) in a model receptor expression system. The novel estrogen fluorophores are based on the rigidified stilbene-like structure of 5,6,11,12-tetrahy...

Topics

Animals
Cells, Cultured
Chrysenes
Estrogens
Fluorescent Dyes
Humans
Ligands
Microscopy, Fluorescence
Mutation
Receptors, Estrogen
Spectrophotometry
Transfection

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