Genotype regulates the development of tolerance to ethanol and cross-tolerance to nicotine.

doi:10.1016/0741-8329(94)90059-0

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Article

Genotype regulates the development of tolerance to ethanol and cross-tolerance to nicotine.

Alcohol (Fayetteville, N.Y.) - 1 Jan 2000

Luo Y, Marks M J, Collins A C

Abstract excerpt

The long-sleep (LS) and short-sleep (SS) mouse lines were selectively bred for differential sensitivity to the anesthetic actions of ethanol, but they also differ in sensitivity to nicotine. A recent study suggested that the LS mice develop more tolerance to ethanol and cross-tolerance to nicotin...

Topics

Absorption
Alcohol Drinking
Animals
Behavior, Animal
Body Temperature
Drug Tolerance
Ethanol
Female
Genotype
Mice
Mice, Mutant Strains
Motor Activity
Nicotine

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