Article
Associations of allelic differences at the A-I/C-III/A-IV gene cluster with carotid artery intima-media thickness and plasma lipid transport in hypercholesterolemic-hypertriglyceridemic humans.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jun 1994
Patsch W, Sharrett A R, Chen I Y, Lin-Lee Y C, Brown S A, Gotto A M, Boerwinkle E
Abstract excerpt
Individuals with elevated levels of plasma cholesterol and triglyceride may be at higher risk for coronary artery disease than those with isolated elevations of either cholesterol or triglyceride. Sequence variation in the A-I/C-III/A-IV gene cluster has been implicated in the etiology of some disorders associated with premature atherosclerosis and/or hypertriglyceridemias with or without elevations of...
Topics
- Adult
- Aged
- Alleles
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins A
- Apolipoproteins C
- Arteriosclerosis
- Biological Transport
- Carotid Artery Diseases