Article
Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype.
Molecular and cellular biology - 1 Jun 1994
Evans S M, Tai L J, Tan V P, Newton C B, Chien K R
Abstract excerpt
The molecular characterization of a cardiac determination gene has been an elusive goal for the past several years. Prior to cloning of the skeletal muscle determination factor MyoD, the presence of a dominantly acting skeletal muscle determination factor had been inferred from the observation th...
Topics
- Animals
- Animals, Newborn
- Atrial Natriuretic Factor
- Cell Line
- Cell Separation
- Embryo, Mammalian
- Fibroblasts
- Fluorescent Antibody Technique
- Heart
- Luciferases
- Mice
- MyoD Protein
- Myocardium
- Phenotype
- Rats
- Transfection
