Article
Mutations in the "dynein regulatory complex" alter the ATP-insensitive binding sites for inner arm dyneins in Chlamydomonas axonemes.
The Journal of cell biology - 1 Jun 1994
Piperno G, Mead K, LeDizet M, Moscatelli A
Abstract excerpt
To understand mechanisms of regulation of dynein activity along and around the axoneme we further characterized the "dynein regulatory complex" (drc). The lack of some axonemal proteins, which together are referred to as drc, causes the suppression of flagellar paralysis of radial spoke and centr...
Topics
- Adenosine Triphosphate
- Animals
- Chlamydomonas
- Dyneins
- Electrophoresis, Gel, Two-Dimensional
- Flagella
- Microtubules
- Molecular Weight
- Mutation
- Protein Binding
